The Ohio State University
Professor, Department of Microbiology, Collage of Arts and Science, The Ohio State University, U.S.
Dr. Stoodley is a professor in the Department of Microbial Infection and Immunity and Orthopaedics at Ohio State University. He also holds an appointment at the University of Southampton in the UK as a professor of Microbial Tribology in the Department of Mechanical Engineering. His specific research focus on biofilms in orthopedic and other device related infections, control of dental biofilms and biofilm mechanics as a surface survival strategy in the context of industrial fouling and medical devices.
The research goal of the Stoodley lab is to identify key processes involved in biofilm development and persistence on the lab bench and in clinical and industrial settings, with the applied aim of improved prevention, diagnostic and treatment strategies. The Stoodley lab takes a broad multidisciplinary approach drawn from clinical medicine, engineering and basic microbiology, to focus on 6 main thrust areas:
1.Influence of genetic and environmental factors on biofilm development and dynamic behavior.
2.Mechanical strength of biofilms and removal strategies.
3.Diagnosis of biofilm infections in orthopaedic and general surgery.
4.Control of dental biofilms.
5.Biofilm monitoring in medicine, industry and natural environments.
6.Development of antibiofilm materials and coatings.
Skills and Expertise:
Biofilms, Antibiotics, Biofilms Formation, Microbiology, Bacteria, Antimicrobials, Environmental Biotechnology, Applied Microbiology, Microbial Molecular Biology, Flow
1.PS190. Howlin, R., Winnard, C., Frapwell, C., Cooper, J., Aiken, S., Stoodley, P. 2016. Biofilm prevention of gram-negative bacterial pathogens involved in periprosthetic infection by antibiotic-loaded calcium sulfate beads in vitro. Biomedical Materials. Dec 2;12(1):015002. IF = 3.361.
2.PS189. Dusane, D., Diamond, S., Knecht, C., Farrar, N., Peters, C., Howlin, R., Swearingen, M., Calhoun, J., Plaut, R.D., Nocera, T., Granger, J., Stoodley, P. 2016. Effects of Loading Concentration, Blood and Synovial Fluid on Antibiotic Release and Anti-Biofilm Activity of Bone Cement Beads. Journal of Controlled Release. IF = 7.705. Revision. 8/22/16.
3.PS188. Stoodley, P. 2016. Evidence for a Biofilm Based Treatment Strategy in the Management of Chronic Hidradenitis Suppurativa. British Journal of Dermatology. IF = 4.275. Accepted 10/3/16.
4.PS187. Malone, M, Goeres, D.M., Gosbell, I., Vickery, K., Jensen, S., Stoodley, P. 2016. Approaches to biofilm-associated infections: The need for standardized biofilm methods for medically relevant clinical applications. Expert Review of Anti-infective Therapy. Accepted 11/16/16. IF = 3.461.
5.PS186. Malone, M., Bjarnsholt, T., McBain, A.J., James, G.A., Stoodley, P., Leaper, D., Tachi M.M., Shultz, G., Swanson, T., Wolcott, R.D. 2016. The prevalence of biofilms in chronic wounds: A systematic review and meta-analysis of published data. Journal of Wound Care. 25(12),000-000. IF2016=1.205. Accepted 11/2/16.