I am a medical microbiologist who has worked for many years in the area of infections of medical devices. My laboratory focuses on development of novel antimicrobials that have applications as antibiotics and disinfectants. We also develop new antimicrobial coatings that can be used for a variety of purposes, including coating of medical devices to reduce associated infections. We have taken several of these through to pre-clinical testing, and antimicrobial contact lenses through to Phase III clinical trials. My laboratory also focusses on the microbiome of the eye and protists that infect the eye (e.g. Acanthamoeba sp.). We have established robust protocols to examine the low biomass microbiome of the ocular surface that can easily be translated for the analysis of other low biomass microbiomes. Within the area of contact lens research, our research includes adhesion and biofilm formation of ocular pathogenic microbes (most notably Pseudomonas aeruginosa and Staphylococcus aureus). This research involves the study of microbial pathogenesis, and mammalian tissue responses to microbes and biomaterials. We have established several animal and cell-based models for studying contact lens adverse events and biomaterial infections.